Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are Differential Activators of Gi

<table>P21 noncentration-dependent displacement of bound 8-OH-DPAT. This curve represents the change in specific binding of [<sup>3</sup>H]-8-OH-DPAT, a 5HT1aR agonist, to the receptor in the presence of various concentrations of the ic2 peptide mimic P21. Nominal binding of agonist at control levels was 400 fmoles/mg protein.</table>

International Journal of Peptides

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Figure 1

Figure 1: Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are Differential Activators of Gi 