International Journal of Peptides / 2012 / Article / Tab 2

Research Article

Modeling the QSAR of ACE-Inhibitory Peptides with ANN and Its Applied Illustration

Table 2

The ACE-inhibitory peptides’ sequences with Z descriptor activity.

PeptideLog(1/IC50) Z 12Z 13Z 21Z 22Z 23

AA3.210.07−1.730.090.07−1.730.09
AW50.07−1.730.09−4.753.650.85
DG1.853.641.132.362.23−5.360.3
GF3.22.23−5.360.3−4.921.30.45
GP3.352.23−5.360.3−1.220.882.23
GR2.492.23−5.360.32.882.52−3.44
GW4.522.23−5.360.3−4.753.650.85
GY3.682.23−5.360.3−1.392.320.01
IF3.03−4.44−1.68−1.03−4.921.30.45
IW5.7−4.44−1.68−1.03−4.753.650.85
IY5.43−4.44−1.68−1.03−1.392.320.01
RF3.642.882.52−3.44−4.921.30.45
RP1.18182.882.52−3.44−1.220.882.23
VG2.96−2.69−2.53−1.292.23−5.360.3
VW1.6−2.69−2.53−1.29−4.753.650.85
VY4.66−2.69−2.53−1.29−1.392.320.01
YG2.7−1.392.320.012.23−5.360.3
RW4.82.882.52−3.44−4.753.650.85
AY4.28−2.69−2.53−1.29−4.921.30.45
RP3.89−4.44−1.68−1.03−1.220.882.23
AF3.720.07−1.730.09−4.921.30.45
AP3.640.07−1.730.09−1.220.882.23
VP3.38−2.69−2.53−1.29−1.220.882.23
IG2.92−4.44−1.68−1.032.23−5.360.3
GI2.922.23−5.360.3−4.44−1.68−1.03
GM2.852.23−5.360.3−2.49−0.27−0.41
GA2.72.23−5.360.30.07−1.730.09
GL2.62.23−5.360.3−4.19−1.03−0.98
AG2.60.07−1.730.092.23−5.360.3
GH2.512.23−5.360.32.411.741.11
KG2.492.841.41−3.142.23−5.360.3
FG2.43−4.921.30.452.23−5.360.3
GS2.422.23−5.360.31.96−1.630.57
GV2.342.23−5.360.3−2.69−2.53−1.29
MG2.32−2.49−0.27−0.412.23−5.360.3
GK2.272.23−5.360.32.841.41−3.14
GE2.272.23−5.360.33.080.39−0.07
GT2.242.23−5.360.30.92−2.09−1.4
WG2.23−4.753.650.852.23−5.360.3
HG2.22.411.741.112.23−5.360.3
GQ2.152.23−5.360.32.180.53−1.14
GG2.142.23−5.360.32.23−5.360.3
QG2.132.180.53−1.142.23−5.360.3
SG2.071.96−1.630.572.23−5.360.3
LG2.06−4.19−1.03−0.982.23−5.360.3
GD2.042.23−5.360.33.641.132.36
TG20.92−2.09−1.42.23−5.360.3
EG23.080.39−0.072.23−5.360.3
PG1.77−1.220.882.232.23−5.360.3
LA3.51−4.19−1.03−0.980.07−1.730.09
KA3.422.841.41−3.140.07−1.730.09
RA3.342.882.52−3.440.07−1.730.09
YA3.34−1.392.320.010.07−1.730.09
FR3.04−4.921.30.452.882.52−3.44
HL2.492.411.741.11−4.19−1.03−0.98
DA2.423.641.132.360.07−1.730.09
EA23.080.39−0.070.07−1.730.09
DM2.77823.641.132.36−2.49−0.27−0.41
IP3.892.92−4.44−1.68−1.220.882.23

* the first number (m) behind Z represents the sequence of the amino acid in peptide, and the second number (n, from 1 to 3) represents the hydrophilic amino acids, three-dimensional shape, size, and electrical parameters, respectively.

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