Research Article

Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea

Figure 3

Sequence alignments of GTx4 (a), GTx5 (b), and GTx6 (c) series. The putative signal sequence deduced by SignalP 3.0 server (http://www.cbs.dtu.dk/services/SignalP/) is indicated by dotted box. Signal sequences of GTx4-7 and signal sequences and prepro-sequences of BsTx, ESTX, and Ba1 are not determined. Mature toxin regions are indicated by closed box in (a) and (b). Conserved cysteine residues are indicated by closed boxes filled with gray color. Accession numbers: GTx4 series, AB201035-AB201036 and AB671312-AB671317; BsTx, P49265; ESTX, P61509; Ba1, P85497; JZTX-48, EU233840; GTx5-1 and GTx5-2, AB201037 and AB683255; JZTX-64, EU233914; HWTX-XVIIIc1, EU195231; HNTX-XVIII-7, GU293118; LSTX-R1, EU926143; GTx6-1, AB201038; HWTX-XVa2, EU195236; JZTX-72, EU233926; Aptotoxin I, P49267.
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(a)
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(b)
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(c)