A Novel Cellular Model to Study Angiotensin II AT2 Receptor Function in Breast Cancer Cells

Figure 4

Binding studies. (a) Competition binding profile for AngII in D3H2LN-AT2 cells. Data are expressed as percentages of the maximum specific binding of the radioligand ³H-AngII. (b) Maximum binding obtained in the presence of the AT1 receptor antagonist (Losartan 10⁻⁶ M) or AT2 receptor antagonist (PD123319 10⁻⁶ M), as compared to the control (vehicle). Values are means ± SE of three independent experiments done in duplicate.

(a)

(b)