Effect of Rabbit Epididymal Antimicrobial Peptide, REHb𝜷P, on LPS-Induced Proinflammatory Cytokine Responses in Human Vaginal Cells In Vitro

Figure 1

Hemoglobin-𝛽 (Hb-𝛽) subunit docked with LPS. Few amino acids in between 110 to 124 of REHb𝛽P showed interaction with LPS. The residues showing interaction are: Ser¹¹⁵, His¹¹⁶, His¹¹⁷, Phe¹¹⁸, Gly¹¹⁹, Glu¹²¹. The N-terminal and C-terminal region forms helical structure with a loop region in between ((a): 3D structure of Hb-𝛽 subunit; (b): interactive amino acids of REHb𝛽P with the LPS are indicated).