Effect of Rabbit Epididymal Antimicrobial Peptide, REHb𝜷P, on LPS-Induced Proinflammatory Cytokine Responses in Human Vaginal Cells In Vitro

Figure 7

Macrophages when induced with LPS, phagocytosis index (PCI) was significantly upregulated over that of cells that were incubated alone either with E. coli or REHb𝛽P or scrambled peptide. LPS-induced macrophages treated with REHb𝛽P (60.61 𝜇M for 1 h) the number of E. coli internalized within macrophages was significantly reduced. Levels of significance (^∗𝑃<0.001 compared with the LPS-induced group, ^∗∗𝑃<0.001 compared with nREHb𝛽P group) were calculated by ANOVA test followed by a Bonferroni analysis.