Total Chemical Synthesis of a Heterodimeric Interchain Bis-Lactam-Linked Peptide: Application to an Analogue of Human Insulin-Like Peptide 3

<table>RP-HPLC and ESI-MS data of ΔA25/26 human INSL3 monolactam A24-B22. (a) RP-HPLC of crude ΔA25/26 human INSL3 A24-B22 <svg height="20.5625" id="M13" style="vertical-align:-3.50803pt" version="1.1" viewbox="0 0 66.6875 20.5625" width="66.6875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> di-Acm species; (b) RP-HPLC of purified ΔA25/26 human INSL3 monolactam A24-B22; (c) ESI-MS of purified ΔA25/26 human INSL3 monolactam A24-B22. HPLC detection wavelength = 220 nm.</table>

International Journal of Peptides

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Figure 3

Figure 3: Total Chemical Synthesis of a Heterodimeric Interchain Bis-Lactam-Linked Peptide: Application to an Analogue of Human Insulin-Like Peptide 3 

Figure 3 | Total Chemical Synthesis of a Heterodimeric Interchain Bis-Lactam-Linked Peptide: Application to an Analogue of Human Insulin-Like Peptide 3 