|
Peptide | Source | Activity | Organisms | Unusual amino acids | References |
|
Discodermin A | Discodermia kiiensis (sponge) | Antifungal | C. albicans | Tert-leucine (t-Leu), cystenoic acid, and sarcosine | [45] |
Jaspamide | Jaspis sp. (sponge) | Antifungal | C. albicans | N-Methyl-2-bromo-D-tryptophan (Me-BrTrp) and L-β-tyrosine (L-βTyr) | [46] |
Theonellamide F | Theonella sp (sponge) | Antifungal | C. albicans | histidinoalanine, 3-Methyl-p-bromophenylalanine, (2S,4R)-2-amino-4-hydroxyadipic acid (L-Ahad), and (3S,4S,5E,7E)-3-amino-4-hydroxy-6-methyl-8-(p-bromophenyl)-5,7-octadienoic acid | [45] |
Cyclolithistide A | T. swinhoei (sponge) | Antifungal | C. albicans | 4-Chloroisoleucine (C1-Ile), 2-amino-pentanoic acid (D-Ape) and 4-amino-3,5-dihydroxyhexanoic acid (Adha) | [47] |
Microsclerodermin A | Theonella sp. (sponge) | Antifungal | C. albicans | (2S,3R,4S,5S,6S,11E)-3-amino-6-methyl-12-(p-Methoxyphenyl)-2,4,5-trihydroxydodec-11-enoic acid (AMMTD), (3R)-4-amino-3-hydroxylbutyric acid (GABOB), and 3-hydroxy-4-amino-5-vinylpyrrolidone. | [48] |
Callipeltin A | Callipelta
sp. (sponge) | Antifungal Antiviral | C. albicans, HIV | (2R,3R,4S)-4-Amino-7-guanidino-2,3-dihydroxyheptanoic acid (AGDHE) | [49] |
Dolastatin 10 | Dolabella auricularia (sea hare), Gymnangium regae (Marine hydroid) | Antifungal | Cryptococcus neoformans | O-demethyldolaproline (Ddap), N-desmethyldolaisoleucine (Ddil), L-threo-phenylserine (L-Pser), and L-guanidino serine (Gser). | [50] |
Nukacin ISK-1 | Staphylococcus warneri ISK-1 | Antibacterial | Gram-positive bacteria | Lanthionine, 3-methyllanthionine, and dehydrobutyrine | [51] |
Mersacidin | Bacillus subtilis | Antibacterial | Gram-positive bacteria | Lanthionine or 3-methyllanthionine | [52] |
Microbisporicin | Microbispora sp | Antibacterial | Gram-positive bacteria | 5-Chloro-trypthopan and mono- (in A2) or bis-hydroxylated (in A1) proline | [53] |
lacticin 3147 | Lactococcus lactis | Antibacterial | Gram-positive bacteria | Lanthionine or β-methyllanthionine | [54] |
Planosporicin | Planomonospora sp | Antibacterial | Gram-positive bacteria | Lanthionine and methyllanthionine | [53] |
Nisin | Lactococcus lactis | Antibacterial | Gram-positive bacteria | Lanthionine methyllanthionine didehydroalanine didehydroaminobutyric acid | [55] |
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