Proteomic Signatures of the Zebrafish (Danio rerio) Embryo: Sensitivity and Specificity in Toxicity Assessment of Chemicals

Figure 2

Microscopically visible lethal effects of Rotenone, DNOC and Diclofenac to eleuthero-embryos studied after 48 h exposure. Concentration-effect relationships based on a logistic model are shown. Parameter estimates were as follows: Rotenone: EC₅₀[𝜇M]=0.068±0.00, 𝑝=8.750±2.25, DNOC: EC₅₀ [𝜇M] = 3.007±0.05, 𝑝=12.311±1.80, Diclofenac: EC₅₀ [𝜇M] = 23.076±1.08, 𝑝=4.746±1.65.