Proteomic Signatures of the Zebrafish (Danio rerio) Embryo: Sensitivity and Specificity in Toxicity Assessment of Chemicals
Figure 5
Summary of results from spot-to-spot analysis of proteomics experiments with Diclofenac (Dic), Rotenone(R), and DNOC (D). For all tested concentrations the percentages of protein spots, related to all detected protein spots in the 2-DE experiment, are depicted that show significant () or highly significant changes () and a minimum of twofold changed expression levels compared to controls. Proteins showing an at least twofold increase in abundance compared to control () are considered as upregulated (oe), all proteins showing an at least twofold decrease in abundance compared to controls are considered as downregulated (rp).
