Comprehensive Proteomic Profiling of Aldehyde Dehydrogenases in Lung Adenocarcinoma Cell Lines

Table 1

Identified Aldehyde Dehydrogenases in the total cell extracts (TCE), Media (Med) and the cell surface (Surf) across 40 lung adenocarcinoma cell lines based on mass spectrometry (MS/MS counts for corresponding peptides).

Gene symbol	Protein description	MS/MS counts (TCE)	MS/MS counts (Med)	MS/MS counts (Surf)	Unique peptides	Chromosome	Length	MW
ALDH16A1	Aldehyde dehydrogenase family 16 member A1	31	79	81	19	19	802	85127
ALDH18A1	Delta-1-pyrroline-5- carboxylate synthase	354	5	344	20	10	795	87302
ALDH1A1	Retinal dehydrogenase 1	4961	2640	1463	37	9	500	54731
ALDH1A2	Retinal dehydrogenase 2	10	1	1	5	15	480	53060
ALDH1A3	Aldehyde dehydrogenase family 1 member A3	1267	256	299	31	15	512	56108
ALDH1B1	Aldehyde dehydrogenase X, mitochondrial	843	22	384	29	9	517	57217
ALDH1L1	Aldehyde dehydrogenase family 1 member L1	5	3	3	8	3	505	55394
ALDH1L2	Aldehyde dehydrogenase family 1 member L2, mitochondrial	11	0	51	15	12	923	101776
ALDH2	Aldehyde dehydrogenase, mitochondrial	4964	889	1665	32	12	517	56381
ALDH3A1	Aldehyde dehydrogenase, dimeric NADP-preferring	1149	44	116	27	17	453	50379
ALDH3A2	Fatty aldehyde dehydrogenase	772	44	457	23	17	485	54848
ALDH3B1	Aldehyde dehydrogenase family 3 member B1	3	0	20	6	11	468	51840
ALDH3B2	Aldehyde dehydrogenase family 3 member B2	3	0	0	2	11	385	42670
ALDH4A1	Delta-1-pyrroline-5- carboxylate dehydrogenase, mitochondrial	256	0	41	22	1	563	61719
ALDH5A1	Succinate-semialdehyde dehydrogenase, mitochondrial	437	8	192	19	6	535	57215
ALDH6A1	Methylmalonate-Semialdehyde dehydrogenase [acylating], mitochondrial	131	0	13	17	14	535	5784
ALDH7A1	Alpha-aminoadipic semialdehyde dehydrogenase	2268	95	563	29	5	510	55235
ALDH8A1	Aldehyde dehydrogenase family 8 member A1	2	0	0	2	6	487	53401
ALDH9A1	4-trimethylaminobutyral dehyde dehydrogenase	1096	98	365	22	1	491	53374