Urine Glycoprotein Profile Reveals Novel Markers for Chronic Kidney Disease
Figure 2
Mass Spectra of glycopeptides derived from Zinc alpha 2 Glycoprotein (a) and Golgi phosphoprotein (b) in CKD urine. Tryptic digests of urine glycoproteins were subjected to LC-ESI-MS/MS analysis as described in Section 2. The mass spectra of peptides DIVEYYNDSNGSHVLQG from zinc alpha 2 glycoprotein which is upregulated (a) and those of peptide AVLVNNITTGER from Golgi phosphoprotein which is significantly downregulated in CKD subjects (b) are shown. The N-linked glycosylation site of each peptide is depicted in red.
