| Location | Function | Gene ontology term | Cluster frequency | -value | FDR | Proteins annotated to the GO Term | Gene ontology term | Cluster frequency | value | FDR | Proteins annotated to the GO term |
| Extracellular region | 18 of 23 proteins, 78.3% | 7.36−15 | 0.00% | EGF, IGHG1, LRG, AMBP, AZGP1, KNG1, SERPING1, TF, LGALS3BP, FETUA, CP, HP, SERPINC1, IGHG2, ORM1, APOD, PTGDS, UMOD | Binding | 20 of 23 proteins, 87.0% | 0.00051 | 0.89% | EGF, IGHG1, AMBP, CUBN, AZGP1, KNG1, SERPING1, TF, LGALS3BP, GAA, FETUA, CP, SERPINC1, HP, IGHG2, GLB1, ORM1, APOD, PTGDS, UMOD | Extracellular space | 11 of 23 proteins, 47.8% | 5.47−11 | 0.00% | EGF, LGALS3BP, CP, FETUA, SERPINC1, APOD, ORM1, PTGDS, UMOD, KNG1, SERPING1 | Protein binding | 15 of 23 proteins, 65.2% | 0.00066 | 0.80% | TF, EGF, IGHG1, LGALS3BP, CP, FETUA, AMBP, HP, SERPINC1, APOD, ORM1, GLB1, CUBN, KNG1, SERPING1 | Extracellular region part | 11 of 23 proteins, 47.8% | 1.13−09 | 0.00% | EGF, LGALS3BP, CP, FETUA, SERPINC1, APOD, ORM1, PTGDS, UMOD, KNG1, SERPING1 | Enzyme regulator activity | 6 of 23 proteins, 26.1% | 0.00024 | 0.00% | EGF, SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Cytoplasmic vesicle | 6 of 23 proteins, 26.1% | 6.81−05 | 0.20% | TF, EGF, CUBN, UMOD, KNG1, SERPING1 | Endopeptidase inhibitor activity | 5 of 23 proteins, 21.7% | 3.78−07 | 0.00% | SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Vesicle | 6 of 23 proteins, 26.1% | 8.57−05 | 0.18% | TF, EGF, CUBN, UMOD, KNG1, SERPING1 | Endopeptidase regulator activity | 5 of 23 proteins, 21.7% | 4.29−07 | 0.00% | SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Cell fraction | 5 of 23 proteins, 21.7% | 0.00405 | 2.29% | EGF, IGHG2, IGHG1, CUBN, AMBP | Peptidase inhibitor activity | 5 of 23 proteins, 21.7% | 4.84−07 | 0.00% | SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Cytoplasmic membrane-bounded vesicle | 5 of 23 proteins, 21.7% | 0.00055 | 0.15% | TF, EGF, CUBN, KNG1, SERPING1 | Peptidase regulator activity | 5 of 23 proteins, 21.7% | 1.10−06 | 0.00% | SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Membrane-bounded vesicle | 5 of 23 proteins, 21.7% | 0.00062 | 0.29% | TF, EGF, CUBN, KNG1, SERPING1 | Enzyme inhibitor activity | 5 of 23 proteins, 21.7% | 8.50−06 | 0.00% | SERPINC1, FETUA, KNG1, AMBP, SERPING1 | Cytoplasmic vesicle part | 4 of 23 proteins, 17.4% | 0.00024 | 0.17% | EGF, CUBN, KNG1, SERPING1 | Transporter activity | 5 of 23 proteins, 21.7% | 0.00527 | 2.88% | CUBN, APOD, AZGP1, PTGDS, AMBP | Stored secretory granule | 4 of 23 proteins, 17.4% | 5.33−05 | 0.22% | TF, EGF, KNG1, SERPING1 | Carbohydrate binding | 3 of 23 proteins, 13.0% | 0.00656 | 2.50% | SERPINC1, GAA, KNG1 | Membrane fraction | 4 of 23 proteins, 17.4% | 0.00796 | 2.69% | IGHG2, IGHG1, CUBN, AMBP | Lipid binding | 3 of 23 proteins, 13.0% | 0.0092 | 2.82% | APOD, AZGP1, PTGDS | Insoluble fraction | 4 of 23 proteins, 17.4% | 0.00897 | 2.81% | IGHG2, IGHG1, CUBN, AMBP | Serine-type endopeptidase inhibitor activity | 3 of 23 proteins, 13.0% | 9.99−05 | 0.00% | SERPINC1, AMBP, SERPING1, E9KL23 | Apical plasma membrane | 3 of 23 proteins, 13.0% | 0.00069 | 0.27% | TF, CUBN, UMOD | Hemoglobin binding | 2 of 23 proteins, 8.7% | 1.36−05 | 0.00% | HP, CUBN | Perinuclear region of cytoplasm | 3 of 23 proteins, 13.0% | 0.00565 | 2.58% | TF, GLB1, PTGDS | Fatty acid binding | 2 of 23 proteins, 8.7% | 0.00076 | 0.73% | AZGP1, PTGDS | Apical part of cell | 3 of 23 proteins, 13.0% | 0.00146 | 0.94% | TF, CUBN, UMOD | Cysteine-type endopeptidase inhibitor activity | 2 of 23 proteins, 8.7% | 0.00084 | 0.83% | FETUA, KNG1 | Lytic vacuole | 3 of 23 proteins, 13.0% | 0.0026 | 1.89% | CUBN, GLB1, GAA | Monocarbox-ylic acid binding | 2 of 23 proteins, 8.7% | 0.00161 | 0.92% | AZGP1, PTGDS | Lysosome | 3 of 23 proteins, 13.0% | 0.0026 | 1.79% | CUBN, GLB1, GAA | Hydrolase activity, hydrolyzing O-glycosyl compounds | 2 of 23 proteins, 8.7% | 0.00354 | 2.29% | GLB1, GAA | Platelet alpha granule lumen | 3 of 23 proteins, 13.0% | 2.55−05 | 0.00% | EGF, KNG1, SERPING1 | Protein kinase regulator activity | 2 of 23 proteins, 8.7% | 0.00418 | 2.13% | EGF, FETUA | Secretory granule lumen | 3 of 23 proteins, 13.0% | 1.37−05 | 0.00% | EGF, KNG1, SERPING1 | Kinase regulator activity | 2 of 23 proteins, 8.7% | 0.00541 | 2.71% | EGF, FETUA | Cytoplasmic membrane-bound vesicle lumen | 3 of 23 proteins, 13.0% | 1.55−05 | 0.00% | EGF, KNG1, SERPING1 | Hydrolase activity, acting on glycosyl bonds | 2 of 23 proteins, 8.7% | 0.0056 | 2.78% | GLB1, GAA | Vesicle lumen | 3 of 23 proteins, 13.0% | 1.74−05 | 0.00% | EGF, KNG1, SERPING1 | Tetrapyrrole binding | 2 of 23 proteins, 8.7% | 0.00841 | 2.67% | CUBN, AMBP | Platelet alpha granule | 3 of 23 proteins, 13.0% | 2.55−05 | 0.00% | EGF, KNG1, SERPING1 | Heparin binding | 2 of 23 proteins, 8.7% | 0.00608 | 2.63% | SERPINC1, KNG1 | Vacuole | 3 of 23 proteins, 13.0% | 0.00423 | 2.27% | CUBN, GLB1, GAA | | | | | | Extrinsic to membrane | 2 of 23 proteins, 8.7% | 0.00532 | 2.61% | CUBN, UMOD | | | | | | Lysosomal membrane | 2 of 23 proteins, 8.7% | 0.00699 | 2.64% | CUBN, GAA | | | | | | Endocytic vesicle | 2 of 23 proteins, 8.7% | 0.00332 | 2.10% | TF, CUBN | | | | | | Coated pit | 2 of 23 proteins, 8.7% | 0.00113 | 0.88% | TF, CUBN | | | | | | Cell projection membrane | 2 of 23 proteins, 8.7% | 0.00899 | 2.71% | CUBN, UMOD | | | | | |
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