Clinical Utility of Serum Autoantibodies Detected by Protein Microarray in Melanoma

Table 3

Univariate associations of glycoproteins with positive nodal status.

Characteristic	Odds ratio	95% CI	P value
ASAH1
500 unit increase	0.685	0.332–1.415	0.306
>1 SD versus not	0.123^†		0.019
CTSD
500 unit increase	0.928	0.869–0.991	0.026
>1 SD versus not	0.106	0.013–0.864	0.022
GRP75
500 unit increase	0.962	0.860–1.076	0.495
>1 SD versus not	0.903	0.266–3.059	0.999
GRP94
500 unit increase	1.076	1.002–1.156	0.0440
>1 SD versus not	38.4^†		<0.0001
LDH
500 unit increase	0.931	0.862–1.007	0.0731
>1 SD versus not	0.193^†		0.0427
Combination: ASAH1, CTSD, and LDH
Any >1 SD versus not	0.173	0.045–0.663	<0.0001

^†Continuity correction applied when calculating the estimate of odds ratios due to cell sample sizes ≤1. Confidence interval not reportable in these cases.