Proteomic Characterization of Cerebrospinal Fluid from Ataxia-Telangiectasia (A-T) Patients Using a LC/MS-Based Label-Free Protein Quantification Technology

Table 2

Overall summary of the proteomic analysis.

Protein priority	Peptide ID confidence	Multiple sequences	Number of proteins	Number of significant changes	Maximum absolute fold-change	Median %CV (replicate)^(a)	Median %CV (rep + sample)^(b)
1	High (>90%)	Yes	204	13	1.52	11.97	19.16
2	High (>90%)	No	273	7	4.30	36.60	47.06
Overall			477	20	4.30	24.29	33.11

^(a)Replicate %CV represents technical variations.
^(b)Rep + sample %CV represents overall variations including both technical and biological variations.