Research Article

Miniaturized Mass-Spectrometry-Based Analysis System for Fully Automated Examination of Conditioned Cell Culture Media

Figure 8

Ratio of 881.45 Da fragment to intact mating factor (1682.84 Da plus 1698.83 Da; right scale). No mating factor or fragments are detected in first 4 investigated time points. At later time points ratios between 0.8 and 2 for culture grown under standard conditions were obtained (right scale, green bars). Note significant reduction of relative amount of 881.45 Da fragments in pepstatin-containing culture (blue bars). Dashed, red curve (left, logarithmic scale) plots growth curve of cells.
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