Table of Contents
International Journal of Proteomics
Volume 2012, Article ID 971907, 14 pages
http://dx.doi.org/10.1155/2012/971907
Research Article

Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome

1Institute of Medical Biology, A*STAR, 8A Biomedical Grove, No. 06-06 Immunos, Singapore 138648
2School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551
3Laboratory of Experimental Cardiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
4The Netherlands Heart Institute, Catharijnesingel 52, 3511 GC Utrecht, The Netherlands
5Cardiovascular Research Institute, and YLL School of Medicine, NUS, Singapore 119074
6Department of Surgery, YLL School of Medicine, NUS, Singapore 119074
7Bioprocessing Technology Institute, A*STAR, Singapore 138671

Received 1 February 2012; Revised 27 March 2012; Accepted 1 June 2012

Academic Editor: John G. Marshall

Copyright © 2012 Ruenn Chai Lai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary material provides the raw data of the detected 20S proteasome in 3 independent batches of exosomes. Supplementary data 1 provides a summary of number of detected peptides in 3 independent batches of exosomes; Supplementary data 2–4 provide the raw data of detected 20S proteasome peptides in 3 independent batches of exosomes respectively; Supplementary data 5–7 provide the Mascot peptide view of unique 20S proteasome peptides in 3 independent batches of exosomes respectively.

  1. Supplementary Materials