An Internal Standard-Assisted Synthesis and Degradation Proteomic Approach Reveals the Potential Linkage between VPS4B Depletion and Activation of Fatty Acid β-Oxidation in Breast Cancer Cells
Figure 3
The role of VPS4B downregulation on the alteration of global protein synthesis and degradation after EGF treatment. Ratios of synthesis rates of SKBR3_shVPS4B versus SKBR3 cells ( axis) are plotted against ratios of degradation rate constants of SKBR3_shVPS4B versus SKBR3 cells ( axis). Diamonds represent ratios of protein expression at 24 hr between the two cell lines, and the relative values of which are indicated on the color scale.
