Comparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug Transporters
Figure 3
Comparison of formation of the monitored peptides (unlabeled (∆) and labeled (filled circle)) during trypsin digestion of OATP1B1 (a), OATP1B3 (b), OATP2B1 (c), and P-gp (d). Data are presented as . At 24 h, additional trypsin was added (see method). Data are as a percent of trypsin digestion at 24 h (mean ± of ).
