Comparative Proteomic Study Reveals the Molecular Aspects of Delayed Ocular Symptoms Induced by Sulfur Mustard
Table 2
MALDI TOF/TOF MS spectrometry protein identification in 2DE map of serum.
Protein name
Accession number
Expression level*
Biological function
value
value
Power
Fold
Max CV%†
MASCOT protein score
Sequence coverage (%)
PI‡
Mw (Da)
Keratin 1
gi∣7331218
Structural proteins
0.00079
0.04
0.99
2
29.8
121
4
8.16
66149
Keratin 10
gi∣186629
0.00079
0.04
0.99
2
29.8
114
5
4.72
39832
Cytokeratin 9
gi∣435476
0.00444
0.09
0.91
1.5
26.34
174
5
5.19
62320
Keratin 1
gi∣7331218
0.00444
0.09
0.91
1.5
26.34
785
16
8.16
66149
Serum albumin
gi∣28592
Molecular carrier and regulator of osmotic pressure in blood
0.00678
0.11
0.86
1.9
36.42
264
6
6.05
71316
Serum albumin
gi∣28592
0.00519
0.12
0.89
2.1
38.32
149
4
6.05
71316
Serum albumin
gi∣28592
0.00284
0.07
0.94
1.8
28.76
308
9
6.05
71316
Serum albumin
gi∣28592
0.00740
0.11
0.85
1.8
31.43
63
2
6.05
71316
Haptoglobin hp2
gi∣223976
Free hemoglobin binding protein in plasma (iron oxidative activity suppressor)
0.00105
0.04
0.98
2.8
44.80
115
6
6.23
42344
Haptoglobin hp2
gi∣223976
0.00372
0.08
0.92
2.3
40.11
70
3
6.23
42344
Haptoglobin hp2
gi∣223976
0.00705
0.11
0.86
3.2
46.62
139
6
6.23
42344
Haptoglobin hp2
gi∣223976
0.00231
0.06
0.95
3.5
79.20
279
11
6.23
42344
Ig kappa
gi∣106529
Immunoglobulin
0.00511
0.10
0.89
1.8
37.77
54
16
5.61
11161
Transferrin
gi∣339469
Iron transport
0.00979
0.13
0.82
1.5
22.25
50
3
8.40
80768
alpha 1 antitrypsin
gi∣177831
protease inhibitor
0.00159
0.05
0.97
1.9
26.26
58
4
4.91
57706
Max CV% is chosen by comparisons of CV% among control and patient groups. *expression level shows protein changes in the patient in comparison with controls. †Maximum of coefficient of variance obtained in comparison between control and patient group. ‡Isoelectric point. Molecular weight in Dalton.
