Research Article
Resolution of Ternary Mixture of Aspirin, Atorvastatin, and Clopidogrel by Chemometric-Assisted UV Spectroscopic and Liquid Chromatography Methods
Table 2
Recovery data obtained for different synthetic mixtures by using the matrix calculation method.
| | Mixture No. | ASP | ATOR | CLOP | | Added (µg) | Found (µg) | Recovery% | Added | Found | Recovery% | Added | Found | Recovery% |
| | 1 | 2.5 | 2.488 | 99.5 | 5.0 | 5.161 | 103.3 | 5.0 | 4.973 | 99.5 | | 2 | 5.0 | 4.875 | 97.5 | 5.0 | 4.900 | 98.0 | 5.0 | 5.165 | 103.3 | | 3 | 7.5 | 7.563 | 100.8 | 5.0 | 5.012 | 100.2 | 5.0 | 4.899 | 98.0 | | 4 | 10.0 | 10.11 | 101.1 | 5.0 | 5.008 | 100.2 | 5.0 | 4.901 | 98.0 | | 5 | 15.0 | 15.21 | 101.4 | 5.0 | 5.014 | 100.3 | 5.0 | 4.890 | 97.8 | | 6 | 20.0 | 19.96 | 99.8 | 5.0 | 4.982 | 99.6 | 5.0 | 5.065 | 101.3 |
| | | | | = 100.0
RSD = 1.44 | | | | | | |
| | 1 | 5.0 | 5.000 | 100.0 | 2.5 | 2.502 | 100.0 | 5.0 | 5.111 | 102.2 | | 2 | 5.0 | 4.875 | 97.5 | 5.0 | 4.900 | 98.0 | 5.0 | 5.165 | 103.2 | | 3 | 5.0 | 4.998 | 100.0 | 7.5 | 7.442 | 99.2 | 5.0 | 5.001 | 100.0 | | 4 | 5.0 | 5.009 | 100.2 | 10.0 | 10.19 | 101.9 | 5.0 | 5.005 | 100.0 | | 5 | 5.0 | 4.875 | 97.5 | 12.5 | 12.58 | 100.6 | 5.0 | 4.962 | 99.2 | | 6 | 5.0 | 5.00 | 100.0 | 17.5 | 17.36 | 99.2 | 5.0 | 4.900 | 98.0 |
| | | | | | | | = 99.8
RSD = 1.35 | | | |
| | 1 | 5.0 | 4.999 | 100.0 | 5.0 | 4.981 | 99.6 | 2.5 | 2.505 | 100.2 | | 2 | 5.0 | 4.875 | 97.5 | 5.0 | 4.900 | 98.0 | 5.0 | 5.165 | 103.3 | | 3 | 5.0 | 5.010 | 100.2 | 5.0 | 4.999 | 100.0 | 7.5 | 7.468 | 99.6 | | 4 | 5.0 | 5.008 | 100.2 | 5.0 | 4.991 | 99.8 | 10.0 | 9.920 | 99.2 | | 5 | 5.0 | 5.002 | 100.0 | 5.0 | 5.005 | 100.0 | 15.0 | 15.301 | 102.0 | | 6 | 5.0 | 4.900 | 98.0 | 5.0 | 5.012 | 100.2 | 20.0 | 20.221 | 101.1 |
| | | | | | | | | | | = 100.9
RSD = 1.55 |
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