Development and Validation of a Discriminating In Vitro Dissolution Method for Oral Formulations Containing Satranidazole

Table 4

Comparison of dissolution profile of two products (A and B) with different ratio of drug : stearic acid.

Time (minutes)	Product A; Drug: stearic acid; (1 : 2)	Product B; Drug: stearic acid; (1 : 1.5)
0	0	0
5	8.71 ± 0.426	8.02 ± 0.512
10	33.9 ± 0.299	52.99 ± 0.69
15	46.05 ± 0.343	62.68 ± 0.489
30	65.83 ± 0.378	73.40 ± 0.397
45	78.57 ± 0.418	81.66 ± 0.434
60	87.65 ± 0.404	90.01 ± 0.546
Similarity factor 𝑓2	46
Difference factor 𝑓1	17