Simple Atomic Absorption Spectroscopic and Spectrophotometric Methods for Determination of Pioglitazone Hydrochloride and Carvedilol in Pharmaceutical Dosage Forms
Table 2
Determination of PGZ-HCl and CRV through ternary complex formation with bismuth tetraiodide by Method A*.
PGZ-HCl
CRV
Procedure 1
Procedure 2
Procedure 1
Procedure 2
Conc. Taken gmL−1
Conc. Found gmL−1
Recovery (%)
Conc. Taken gmL−1
Conc. Found gmL−1
Recovery (%)
Conc. Taken µgmL−1
Conc. Found gmL−1
Recovery (%)
Conc. Taken µgmL−1
Conc. Found gmL−1
Recovery (%)
5
4.88
97.53
15
15.20
101.31
10
9.87
98.72
16
16.04
100.28
10
9.94
99.41
25
24.99
99.94
25
25.12
100.48
24
24.13
100.55
15
15.01
100.04
35
34.92
99.76
40
40.10
100.25
40
39.50
98.75
25
25.14
100.54
45
44.92
99.81
60
60.16
100.27
48
47.81
99.60
35
35.27
100.76
55
55.34
100.61
70
69.52
100.32
56
56.12
100.21
45
45.03
100.07
65
65.13
100.19
80
80.22
100.28
72
71.93
99.90
50
49.74
99.47
Mean
99.69
100.27
99.98
99.88
±SD
1.07
0.59
0.7
0.64
±RSD
1.07
0.59
0.7
0.64
SE
0.41
0.24
0.29
0.26
Variance
1.15
0.35
0.49
0.41
Slope
2.7642
0.0143
3.7383
0.0136
LOD gmL−1
1.82
2.66
3.10
5.85
LOQ gmL−1
5.53
8.06
9.39
14.71
Sandell’s sensitivity gcm−2
0.000103
0.067
0.000171
0.096
Apparent Molar absorptivity LMol−1cm−1
383.01
0.59
229.59
Average of three different trials of determinations.
