Interaction of Small Zinc Complexes with Globular Proteins and Free Tryptophan

Table 3

Summary of binding constant, , binding site number, , and for BSA, HSA, lysozyme, and free tryptophan at 25°C.

Complex	BSA			HSA			Lysozyme			Free Trp
	/M^−1		/kJ mol^−1	/M^−1		/kJ mol^−1	/M^−1		/kJ mol^−1	/M^−1		/kJ mol^−1
3	1.2 × 10^5	1.0	−29	7.7 × 10^10	2.5	−56	6.2 × 10^4	1.0	−27	—	—	—
4	—	—	—	2.0 × 10^6	2.5	−66	3.7 × 10^4	1.0	−26	1.2 × 10^5	1.0	−29
5	1.1 × 10^6	1.0	−35	5.0 × 10^6	1.5	−38	1.7 × 10^7	2.0	−41	—	—	—
6	9.6 × 10^4	1.0	−28	—	—	—	—	—	—	—	—	—