Table of Contents
International Journal of Tissue Engineering
Volume 2013, Article ID 198762, 15 pages
Research Article

Engineered Human Muscle Tissue from Skeletal Muscle Derived Stem Cells and Induced Pluripotent Stem Cell Derived Cardiac Cells

1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA
2Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
3Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
4Department of Developmental Biology, University of Pittsburgh, Pittsburgh, PA 15224, USA
5McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA
6Rangos Research Center, Room 8121, 4401 Pennsylvania Avenue, Pittsburgh, PA 15224, USA

Received 30 May 2013; Revised 19 September 2013; Accepted 28 September 2013

Academic Editor: Tianqing Liu

Copyright © 2013 Jason Tchao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The video shows synchronous spontaneous intracellular calcium transients in two adjacent cells within MDSC-EMT. This suggests that the cells are electrically coupled. Calcium transients were visualized using Rhod2-AM calcium dye.

  1. Supplementary Material