Table of Contents
Influenza Research and Treatment
Volume 2010 (2010), Article ID 642492, 7 pages
Research Article

Ten-Year (1999–2009) Epidemiological and Virological Surveillance of Influenza in South Italy (Apulia)

1Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Via Prov. Le Lecce-Monteroni 73100 Lecce, Italy
2Department of Clinical and Experimental Medicine, Section of Hygiene and Occupational Health, University of Ferrara, Via Fossato Di Mortara, 24 44121 Ferrara, Italy
3Department of Biomedical Sciences, Hygiene Section, University of Bari, Apulia Regional Epidemiological Observatory, Piazza Giulio Cesare 70100, Bari, Italy

Received 14 December 2009; Accepted 12 April 2010

Academic Editor: Bruno Lina

Copyright © 2010 Annamaria Campa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Clinical and epidemiological surveillance of influenza and other Acute Respiratory Infections (ARI) are currently a major objective of Public Health. The aim was to describe the epidemiology of influenza using the Italian surveillance system. Vaccination Coverage (VC) rates were calculated during 1999-2009 influenza seasons. Molecular studies of influenza virus isolated, from patients with ILI, living in Apulia, are described. 1269 nasal-pharyngeal swabs were taken from patients with ILI and ARI in order to isolate and identify viruses using PCR. Influenza isolates are typed as being types A and B and influenza A isolates are A/H1 and A/H3. The progression of the ILI cases registered in Apulia was similar to the data recorded on a national level. The VC data recorded in Apulia showed a progressive increase in the vaccine doses administered to subjects over 65 years old. The virological surveillance showed a major circulation of the type A/H3N2 influenza virus during the peak incidence of the illness in seasons 1999-2000, 2002-2003, 2004-2005 and 2008-2009. During the same period, the lowest incidence was registered when the type A/H1N1 and B viruses were in circulation. In contrast, during the other seasons the lowest incidence was reported with A/H3N2 and B viruses.