Table of Contents
Influenza Research and Treatment
Volume 2011, Article ID 285218, 7 pages
http://dx.doi.org/10.1155/2011/285218
Research Article

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys

1Division of Avian Diseases, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel
2Yeffe-Hod, Turkey Breeding Farms and Hatcheries, Kvutzat Yavne, P.O Evtach, 79233, Israel
3Israel Veterinary Services, Southern Diagnostic Laboratory for Poultry, Beer Tuvia 79540, Israel

Received 10 August 2010; Revised 30 November 2010; Accepted 13 December 2010

Academic Editor: Mikhail Matrosovich

Copyright © 2011 I. Shkoda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.