Table of Contents
ISRN Cardiology
Volume 2011, Article ID 134631, 3 pages
http://dx.doi.org/10.5402/2011/134631
Case Report

Thrombotic Occlusion of All Left Coronary Branches in a Young Woman with Severe Ulcerative Colitis

1Department of Cardiology, Skane University Hospital Malmoe, 20502 Malmoe, Sweden
2Department for Coagulation Disorders, Skane University Hospital Malmoe, 20502 Malmoe, Sweden
3Department of Gastroenterology, Skane University Hospital Lund, 22185 Lund, Sweden
4Department of Radiology, Helsingborg Hospital, 25187 Helsingborg, Sweden
5Department of Internal Medicine, Central Hospital, Halmstad Hospital, 30185 Halmstad, Sweden
6Private Practice, Upplandsgatan 16, 21429 Malmoe, Sweden
7Department of Internal Medicine, Helsingborg Hospital, 25187 Helsingborg, Sweden

Received 28 February 2011; Accepted 7 April 2011

Academic Editors: J. Morais, I. Ott, and F. Perticone

Copyright © 2011 Carl Gunnar Gustavsson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The thrombosis risk is increased in active ulcerative colitis. The limited number of reported complications have predominantly been cerebrovascular but other vessel territories may also be affected. Patient. During a severe attack of ulcerative colitis a 37-year-old woman suffered occlusion of all left coronary artery branches. Serial angiographies showed progressive recanalisation of the coronary arteries during anticoagulation, but no atherosclerotic stenosis. The cause of infarction was thus considered to be an extensive coronary thrombosis. However, a large battery of blood tests failed to identify any procoagulant abnormality. Conclusion. Evidence is now accumulating that the increased thrombosis risk also may involve the coronary arteries, even in young patients. To the best of our knowledge this is the third reported case of myocardial infarction despite angiographically normal coronary arteries in a patient with active ulcerative colitis. The extent of affected myocardium was in this case exceptionally large.