Antitumor Activity of Citrus maxima (Burm.) Merr. Leaves in Ehrlich's Ascites Carcinoma Cell-Treated Mice

Table 1

Effect of MECM on survival time, increased life span, tumor volume, viable cell count, and nonviable cell count of EAC tumor bearing mice (𝑛=6).

Parameters	EAC control	200 mg/kg MECL	400 mg/kg MECL	20 mg/kg 5-FU
Tumor volume (mL)	3.8 ± 0.26	2.15 ± 0.44*	1.56 ± 0.22*	0.73 ± 0.18*
MST (days)	19.5	28	34	40.5
%ILS	0	43.59	74.36	107.69
Viable cell ×10^7	7.47 ± 0.14	1.71 ± 0.06*	1.39 ± 0.15*	0.93 ± 0.04*
Nonviable cell ×10^7	0.32 ± 0.03	1.6 ± 0.04**	2.34 ± 0.05**	2.72 ± 0.05**
Total cell ×10^7	7.79	3.31	3.73	3.65
Viable%	95.89	51.66	37.27	25.48
Nonviable%	4.11	48.34	62.73	74.52

*Experimental groups are compared with control group (𝑃<.001).
**Experimental groups are compared with control group (𝑃<.05).