Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011, Article ID 146264, 9 pages
http://dx.doi.org/10.5402/2011/146264
Review Article

Management of Women with Surgically Staged 1 Uterine Papillary Serous Cancer

1Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada L8N 3Z5
2Department of Gynecologic Oncology, St. Augustinus Hospital, L8V 5C2 Antwerp, Belgium

Received 20 May 2011; Accepted 6 July 2011

Academic Editors: L. Gebrim, E. Petru, and L. B. Twiggs

Copyright © 2011 Laurie Elit et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To review the management and outcomes of women with surgically staged 1 UPSC. Methods. We report on a case series from 2008–2010 from Hamilton Canada. We summarize the data from a literature search on surgically staged 1 UPSC. Results. There is a group women with Stage 1A UPSC with no residual disease at time of surgery who do not require adjuvant therapy. Vault recurrences appear to be lower in women who received adjuvant vault radiation. Chemotherapy appears to confer longer survival for those women with Stage 1B or 1C disease compared of those observed or who had radiation alone. Conclusion. Adjuvant therapy appears to confer benefit in certain groups of women with stage 1 UPSC. A randomized controlled study would clarify the degree of benefit.