Table of Contents
ISRN Pediatrics
Volume 2011, Article ID 175931, 4 pages
Case Report

Neonatal Cyanosis: Diagnostic and Management Challenges

Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, USA

Received 8 November 2010; Accepted 6 December 2010

Academic Editors: A. Shuper and T. F. Yeh

Copyright © 2011 A. Izraelit et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Neonatal central cyanosis is always a sign of serious pathological processes and may involve diverse organs and impose a significant diagnostic and therapeutic challenge. Here, we report an unusual presentation of Ebstein's anomaly, a rare congenital heart malformation, as the cause of central cyanosis in a one-week-old full-term infant. Initiation of PEG1 therapy in neonates with Ebstein's anomaly always needs a very careful consideration because of a high risk for the development of a “circular shunt” leading to severe deterioration of multiple organs perfusion.