Research Article

Assessment of Styrene Oxide Neurotoxicity Using In Vitro Auditory Cortex Networks

Table 1

Percent average spike rate reduction with acute application of DMSO and SO (maximum DMSO = 3%).

ConcentrationsPercent activity decreasePercent difference
SO (mM)DMSO (%)DMSO only ( 𝑛 = 3 )SO in DMSO ( 𝐧 = 𝟏 𝟎 ) (SO effect)

0.10.1 1 0 . 8 ± 5 . 9 1 7 . 6 ± 3 . 3 6.8
0.250.25 1 3 . 1 ± 8 3 2 . 7 ± 6 . 6 19.6
0.50.5 1 7 . 1 ± 2 . 7 4 5 . 9 ± 4 . 1 28.8
1.01.0 2 5 . 9 ± 6 . 4 5 9 . 5 ± 6 . 2 33.6
2.02.0 3 6 . 5 ± 7 7 6 . 2 ± 7 . 6 39.6
3.03.0 3 9 . 8 ± 8 . 1 8 1 . 1 ± 7 . 7 41.3