Table of Contents
ISRN Cardiology
Volume 2011, Article ID 215627, 7 pages
Research Article

Aorta Fluorescence Imaging by Using Confocal Microscopy

1Biophotonics Interdisciplinary Research Center and Institute of Biophotonics, National Yang-Ming University, Taipei 11221, Taiwan
2Department of Photonics, National Chiao Tung University, Hsinchu 30010, Taiwan
3Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei 10617, Taiwan
4Institute of Biomedical Engineering, National Taiwan University, Taipei 10051, Taiwan

Received 17 March 2011; Accepted 3 May 2011

Academic Editors: E. A. Bocchi, M. Saeed, and C. Vassalle

Copyright © 2011 Chun-Yang Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The activated leukocyte attacked the vascular endothelium and the associated increase in VEcadherin number was observed in experiments. The confocal microscopic system with a prism-based wavelength filter was used for multiwavelength fluorescence measurement. Multiwavelength fluorescence imaging based on the VEcadherin within the aorta segment of a rat was achieved. The confocal microscopic system capable of fluorescence detection of cardiovascular tissue is a useful tool for measuring the biological properties in clinical applications.