The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia

Table 3

Distribution of symptoms being relieved in relation to specific medication.

Symptoms	Patients	Drug	Patients before treatment	Percentage before treatment	Patients whom their symptoms relieved	Percentage of whom their symptoms relieved	𝑃-value*
Abdominal; pain	169	Cimetidine	37	21.9	17	45.9	<.05
		Famotidine	36	21.3	24	66.7
		Omeprazole	52	30.8	38	73.1
		Ranitidine	44	26	29	65.9
Epigastric; pain	89	Cimetidine	21	23.6	6	28.6	<.05
		Famotidine	19	21.3	13	68.4
		Omeprazole	30	33.7	20	66.7
		Ranitidine	19	21.3	13	68.4
Periumbilical pain	95	Cimetidine	20	21	11	55	>.05
		Famotidine	17	17.9	11	64
		Omeprazole	31	32.6	23	74
		Ranitidine	27	28.5	16	59
Nausea	87	Cimetidine	20	23	18	90	>.05
		Famotidine	13	15	11	84
		Omeprazole	33	38	29	87.8
		Ranitidine	21	24	17	80.9
Vomiting	47	Cimetidine	10	21.3	9	90	>.05
		Famotidine	8	17	6	75
		Omeprazole	17	36.2	12	70.6
		Ranitidine	12	25.5	11	91.7
Anorexia	87	Cimetidine	18	20.7	8	44.4	>.05
		Famotidine	24	27.6	12	50
		Omeprazole	24	27.6	13	54.2
		Ranitidine	21	24	13	61.9
Early satiety	54	Cimetidine	15	27.8	10	66.7	>.05
		Famotidine	12	22	6	50
		Omeprazole	13	24	11	84.6
		Ranitidine	14	25.6	8	57.1
Heart burn	39	Cimetidine	6	15.4	3	50	>.05
		Famotidine	8	20.5	7	87.5
		Omeprazole	19	48.7	16	54.2
		Ranitidine	6	15.4	5	83.3
Chest pain	19	Cimetidine	5	26.3	2	40	>.05
		Famotidine	2	10.5	2	100
		Omeprazole	8	42	6	75
		Ranitidine	4	21	3	75
Halitosis	129	Cimetidine	27	21	7	25.9	>.05
		Famotidine	29	22.5	13	44.8
		Omeprazole	40	31	21	52.5
		Ranitidine	33	25.6	17	51.5
Nocturnal awakening	76	Cimetidine	16	21	9	56.3	>.05
		Famotidine	18	23.7	14	77.7
		Omeprazole	24	31.6	18	75
		Ranitidine	18	23.7	13	72.2

* The 𝑃-value is indicative of comparison between various medications effectiveness with each symptom relief.