Table of Contents
ISRN Pulmonology
Volume 2011 (2011), Article ID 257979, 6 pages
http://dx.doi.org/10.5402/2011/257979
Research Article

High Salt Intake and Risk of Chronic Bronchitis: The Copenhagen Male Study—A 10-Year Followup

1The Copenhagen Male Study, Epidemiological Research Unit, Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, Denmark
2Research Centre for Prevention and Health, Glostrup University Hospital, Copenhagen, Denmark

Received 27 April 2011; Accepted 27 June 2011

Academic Editors: A. Kurdowska, A. Miyazato, and T. Seemungal

Copyright © 2011 Poul Suadicani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. The role of salt intake as a risk factor for asthma, bronchial hyperresponsiveness, and other bronchial symptoms has been addressed in a number of studies. Collectively, these studies indicate an increased risk of bronchial symptoms with high consumption of salt, but the issue remains controversial. We tested prospectively the hypothesis that salt intake would be an independent risk factor for chronic bronchitis (CB). Design. A 10-year prospective study of 2,183 men aged 46 to 65 years without any relevant lung symptoms at baseline. Main Outcome. Chronic bronchitis. Results. During the 10-year followup, the overall incidence of CB was 7.1% among men without any relevant lung symptoms at baseline. In a multiple logistic regression analysis, controlling for age, smoking habits, occupational dust exposure, alcohol use, and social class, the odds ratio associated with self-assessed high salt preference (reported by 24%) was 1.6 (1.1–2.4). Interpretation. The results suggest that salt restriction may prevent chronic bronchitis.