Table of Contents
ISRN Endocrinology
Volume 2011, Article ID 259392, 5 pages
http://dx.doi.org/10.5402/2011/259392
Case Report

Intrasellar Chondroid Chordoma: A Case Report

1Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil
2Department of Pathology, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil
3Division of Neurosurgery, Department of Neurology, Psychology and Psychiatry, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil

Received 15 December 2010; Accepted 3 January 2011

Academic Editors: A. De Bellis, J. A. Rillema, and O. Serri

Copyright © 2011 Renata M. Hirosawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chordomas are tumors derived from cells that are remnants of the notochord, particularly from its proximal and distal extremes, they are mainly midline and represent approximately 1% of all malignant bone tumors and 0.1 to 0.2% of intracranial neoplasms. Chordomas involving the sellar region are rare. Herein, we describe a 57-year-old male patient presenting with a history of retro-orbital headache, progressive loss of vision, and clinical features of hypopituitarism, for over 2 months. During evaluation, the CT scan revealed a large contrast-enhancing intrasellar tumor with a 3.6-cm largest diameter. The patient underwent transsphenoidal partial resection of the tumor, and histological examination was consistent with the diagnosis of chondroid chordoma. Although chordomas are rare, they may be considered to constitute a differential diagnostic of pituitary adenomas, especially if a calcified intrasellar tumor with bone erosion is diagnosed.