Table of Contents
ISRN Pharmaceutics
Volume 2011 (2011), Article ID 276250, 8 pages
http://dx.doi.org/10.5402/2011/276250
Research Article

Formulation and Evaluation of Floating Oral In Situ Gelling System of Amoxicillin

Department of Pharmaceutics, Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana, Gujarat 384 001, India

Received 31 March 2011; Accepted 8 May 2011

Academic Editors: F. Fernández and G. Ragno

Copyright © 2011 Dasharath M. Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. S. Ramakrishna, “Helicobacter pylori infection in India: the case against eradication,” Indian Journal of Gastroenterology, vol. 25, no. 1, pp. 25–28, 2006. View at Google Scholar · View at Scopus
  2. G. H. Joel and E. L. Lee, “Agents for control of gastric acidity and treatment of peptic ulcers,” in The Pharmacological Basis of Therapeutics, A. G. Gilman, J. G. Hardman, and L. E. Limbird, Eds., pp. 909–910, The MC Graw Hill, New York, NY, USA, 2001. View at Google Scholar
  3. T. A. Manuel and V. R. Leopoldo, “Assay of amoxicillin sustained release from matrix tablets containing different proportions of Carbopol 971P NF,” International Journal of Pharmaceutics, vol. 273, no. 1-2, pp. 121–127, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. A. K. Hilton and P. B. Deasy, “In vitro and in vivo evaluation of an oral sustained-release floating dosage form of amoxycillin trihydrate,” International Journal of Pharmaceutics, vol. 86, no. 1, pp. 79–88, 1992. View at Publisher · View at Google Scholar · View at Scopus
  5. N. G. Sonani, S. P. Hiremath, and S. A. Sreenivas, “Design and evaluation of gastroretentive mucoadhesive cephalexin tablets,” Pharmaceutical Development and Technology, vol. 15, no. 2, pp. 178–183, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. N. H. Nagahara, A. M. Yohko, N. Masafumi, and T. Mayumi, “Mucoadhesive microspheres containing amoxicillin for clearance of H. pylori,” American Society for Microbiology, vol. 42, no. 10, pp. 2492–2494, 1998. View at Google Scholar
  7. S. Miyazaki, N. Kawasaki, and M. Kubo, “Comparison of in situ gelling formulations for the oral delivery of cimetidine,” International Journal of Pharmaceutics, vol. 220, no. 1-2, pp. 161–168, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. N. K. Ali and T. Anish, “In situ cross-linking of sodium alginate with calcium and aluminum ions to sustain the release of theophylline from polymeric matrices,” Farmaco, vol. 59, no. 12, pp. 999–1004, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. N. M. Harish, P. Prabhu, and N. Charyulu, “Formulation and evaluation of in situ gels containing clotrimazole for oral candidiasis,” Indian Journal of Pharmaceutical Sciences, vol. 71, no. 4, pp. 421–427, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. K. B. Wataru, M. Shozo, D. Masatake, and T. Mitsuo, “Oral sustained delivery of ambroxol from in situ-gelling pectin formulations,” International Journal of Pharmaceutics, vol. 271, no. 1-2, pp. 233–240, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. USP 24 and NF 19. Rockville, MD: United State Pharmacopoeial Convention, Inc. 2000, 1941.
  12. G. A. Lewis, “Optimization methods,” in Encyclopaedia of Pharmaceutical Technology, J. Swarbrick and J. C. Boylan, Eds., pp. 2458–2468, Marcel Dekker, New York, NY, USA, 1996. View at Google Scholar
  13. T. Higuchi, “Mechanism of sustained action mediation, theoretical analysis of rate of release of solid drugs dispersed in solid matrices,” Journal of Pharmaceutical Sciences, vol. 52, pp. 1145–1149, 1963. View at Google Scholar
  14. A. W. Hixon and J. H. Crowell, “Dependence of reaction velocity upon surface and agitation,” Industrial & Engineering Chemistry Research, vol. 23, pp. 923–931, 1931. View at Google Scholar
  15. R. W. Korsmeyer, R. Gurny, E. Doelker, P. Buri, and N. A. Peppas, “Mechanisms of solute release from porous hydrophilic polymers,” International Journal of Pharmaceutics, vol. 15, no. 1, pp. 25–35, 1983. View at Publisher · View at Google Scholar · View at Scopus
  16. P. Coasta, J. Manuel, and S. Labao, “Modelling and comparision of dissolution profiles,” European Journal of Pharmaceutical Sciences, vol. 13, pp. 123–133, 2002. View at Google Scholar
  17. W. Mendenhall and T. Sincich, “Multiple regression,” in A second Course in Business Statistics, Regression Analysis, pp. 141–226, Dellen Publishing, San Francisco, Calif, USA, 1989. View at Google Scholar
  18. J. Siepmann and N. A. Peppas, “Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC),” Advanced Drug Delivery Reviews, vol. 48, no. 2-3, pp. 139–157, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. P. L. Ritger and N. A. Peppas, “A simple equation for description of solute release II. Fickian and anomalous release from swellable devices,” Journal of Controlled Release, vol. 5, no. 1, pp. 37–42, 1987. View at Google Scholar · View at Scopus