Research Article

Formulation and Evaluation of Floating Oral In Situ Gelling System of Amoxicillin

Table 5

Calculations for testing the model in portions.

DFSSMS 𝐹 𝑅 2

For floating lag time

Regression
 FM585.7717.154.130.87 𝐹 c a l c . = 0 . 7 3
𝐹 t a b l e = 9 . 1 2
DF = (4,3)
 RM173.573.520.810.002
Error
 FM312.444.15
 RM724.723.53

For 𝑄 6

Regression
 FM5327.4265.488.710.935 𝐹 c a l c . = 3 . 3 6
𝐹 t a b l e = 9 . 1 2
DF = (4,3)
 RM1226.44226.4412.830.64
Error
 FM322.547.51
 RM7123.5117.64

For 𝑄 1 0

Regression
 FM5325.3765.077.830.92 𝐹 c a l c . = 3 . 9 9
𝐹 t a b l e = 9 . 1 2
DF = (4,3)
 RM1192.66192.660.55
Error
 FM312.444.15
 RM724.723.53

DF indicates the degree of freedom; SS: Sum of squares; MS: Mean of squares; 𝑅 2 : Regression coefficient; FM: Full model; RM, Reduced model. 𝑄 6 and 𝑄 1 0 indicate percentage of drug released after 6 and 10 h, respectively.