Research Article
Formulation and Evaluation of Floating Oral In Situ Gelling System of Amoxicillin
Table 6
Kinetic treatment of dissolution data.
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| Zero order | | | | | | | | | | | 5.17 | 5.27 | 5.42 | 5.45 | 5.44 | 5.89 | 5.78 | 4.59 | 4.42 | | 47.48 | 45.72 | 43.66 | 43.52 | 42.24 | 37.46 | 38.33 | 40.13 | 40.10 | | 0.9619 | 0.9713 | 0.9716 | 0.9692 | 0.9771 | 0.9844 | 0.9811 | 0.9969 | 0.9941 | First order | | | | | | | | | | | 0.030 | 0.031 | 0.033 | 0.033 | 0.033 | 0.036 | 0.035 | 0.029 | 0.029 | | 1.699 | 1.686 | 1.668 | 1.667 | 1.657 | 1.619 | 1.626 | 1.637 | 1.634 | | 0.9465 | 0.9554 | 0.9527 | 0.9496 | 0.9604 | 0.9702 | 0.9666 | 0.9874 | 0.9812 | Higuchi | | | | | | | | | | | 24.07 | 24.42 | 25.13 | 25.31 | 25.14 | 27.02 | 26.50 | 20.73 | 20.04 | | 22.88 | 20.91 | 18.09 | 17.74 | 16.81 | 10.41 | 11.76 | 19.70 | 20.54 | | 0.9832 | 0.9880 | 0.9892 | 0.9877 | 0.9905 | 0.9893 | 0.9873 | 0.9897 | 0.9901 | Hixon Crowell | | | | | | | | | | | −0.09 | −1.75 | −1.80 | −1.81 | −1.83 | −1.96 | −1.92 | −1.52 | −1.47 | | 0.973 | 18.09 | 18.77 | 18.82 | 19.25 | 20.84 | 20.55 | 19.95 | 19.97 | | −0.9525 | −0.9713 | −0.9715 | −0.9691 | −0.9775 | −0.9843 | −0.9810 | −0.9969 | −0.9940 | Korsemeyer and Peppas | | | | | | | | | | | 0.333 | 0.341 | 0.361 | 0.364 | 0.363 | 0.396 | 0.387 | 0.316 | 0.313 | | −0.34 | −0.355 | −0.376 | −0.378 | −0.385 | −0.423 | −0.416 | −0.395 | −0.399 | | 0.9845 | 0.9857 | 0.9885 | 0.9868 | 0.9877 | 0.9802 | 0.9756 | 0.9832 | 0.9859 |
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= slope, = intercept, = Square of correlation coefficient, and = diffusion exponent.
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