Novel Vitamin D Analogs for Prostate Cancer Therapy

<table>Julia coupling reaction between the A-ring C5 and the CD-ring C6 positions. TBS: <i>tert</i>-butyldimethylsilyl group as a protecting group, MOM: methoxymethyl group as a protecting group, LiHMDS: lithium hexamethyldisilazide, THF: tetrahydrofuran, (+)-CSA: (+)-10-camphorsulfonic acid. The structures are written with steroidal numbering.</table>

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Figure 2

Figure 2: Novel Vitamin D Analogs for Prostate Cancer Therapy 