Mgat5 Deficiency in T Cells and Experimental Autoimmune Encephalomyelitis

Table 1

Clinical observations of adoptive transfer EAE.

Genotype	𝑛	Mean High Score	Incidence		Day of Onset	Mean Duration (Days)
		(Mean ± SEM)	(Day 20)	(Day 40)	(Mean ± SEM)	(Mean ± SEM)
		𝑃=0.009				𝑃=0.014
𝑀𝑔𝑎𝑡5^+/+	7	0.3±0.2	0%	0%	9.5±1.5	3.4 ± 2.6
𝑀𝑔𝑎𝑡5^−/−	8	1.5±0.3	63%	38%	7.3±1.8	20.8 ± 4.9

Mice were scored daily on a scale of 0–5 with: 0, no disease; 1: loss of tail tone; 2: hindlimb weakness; 3: hindlimb paralysis; 4: forelimb weakness or paralysis and hindlimb paralysis; 5: moribund or dead. 𝑃 values for EAE mean high score and disease duration were determined by the Mann-Whitney test.