Degradable PHBHHx Modified by the Silk Fibroin for the Applications of Cardiovascular Tissue Engineering

Figure 3

Diffusion curve of water in PHBHHx (HHx = 12 mol%) matrix with crystalline degree of 16.2±0.3%. The hollow square and solid triangle points represent experimental data of Sample I and II, respectively, and the solid lines represent fitted curves based on Fickian Model. The thickness of the polymer film 𝐿=97±1 μm. (a) represents 𝑣(OH) stretching band at 3700~3000 cm⁻¹  versus diffusion time; (b) represents 𝛿(OH) bending band at 1700~1550 cm⁻¹  versus diffusion time. The diffusion coefficient 𝐷_𝑣 derived from 𝑣(OH) stretching band is 8.7×10⁻⁸ cm² s⁻¹ (Sample I, 𝑅^2𝑣=0.9994) and 7.5×10⁻⁸ cm² s⁻¹ (Sample II, 𝑅^2𝑣=0.9990) and 𝐷_𝛿 derived from 𝛿(OH) bending band is 8.1×10⁻⁸ cm² s⁻¹ (Sample I, 𝑅^2𝛿=0.9990) and 7.0×10⁻⁸ cm² s⁻¹ (Sample II, 𝑅^2𝛿=0.9992) at 293 K. The average water diffusion coefficient 𝐷 and standard deviation of 7.8±0.7×10⁻⁸ cm² s⁻¹ was determined by two pairs of 𝐷_𝑣 and 𝐷_𝛿 [22].

(a)

(b)