Clinical Study

In Vivo Ciprofloxacin Release from Hydroxyapatite-Based Bone Implants in Rabbit Tibia: A Preliminary Study

Table 1

Drug concentration and drug loading in the synthesized HAp-ciprofloxacin composites by precipitation technique.

Synthesis parametersDrug concentrationaDrug loadinga
CiprofloxacinStirring speedOrthophosphoric acid addition rate

2 grams600 rpm0.5 mL/minute 6 4 . 1 0 ± 0 . 6 0 % w/w 8 6 . 6 0 ± 5 . 7 0 % w/w

aMean ± Standard Deviation, 𝑛 = 3 .