Review Article

Immunopathogenesis in Chlamydia trachomatis Infected Women

Table 1

Presence of Toll-like receptors (TLRs) and nucleotide-binding oligomerization domains (NODs) in the genital tract.

PRRsPAMPsPresence in genital tract
In vivo In vitro

TLR2Peptidoglycan++
TLR4LPS and hsp++
TLR9Bacterial DNANT+
NOD1PeptidoglycanNTNT
NOD2Peptidoglycan LPSNTNT

Modified from den Hartog et al. 2006 [3].
Legenda: hsp: heat shock protein; LPS: lipopolysaccharide; NT: not tested; PAMPs: pathogen-associated molecular patterns; PRRs: pattern recognition receptors.