Next Generation Cancer Protection: The Bivalent HPV Vaccine for Females

Table 2

Vaccine composition of a 0.5 mL dose of Cervarix [63].

	Protein subunit component	Concentration	Adjuvant	Manufacturing components	Expression system
Cervarix	HPV 16 L1 VLP	20 μg	AS04: 50 μg of 3-O-desacyl-4′-mono; phosphoryl lipid A (MPL) adsorbed onto 500 μg aluminum hydroxide salt	4.4 mg sodium chloride	Baculovirus expression system in Trichoplusia ni insect cells
	HPV 18 L1 VLP	20 μg		0.624 mg sodium dihydrogen phosphate dihydrate; <40 ng of insect cell and viral protein; <150 ng bacterial cell protein