Meibomian Gland Dysfunction: Endocrine Aspects

Table 4

Descriptive statistics of serum hormone levels with respect to genders disclosing statistically significant differences of mean values between patients with seborrheic meibomian gland dysfunction and controls.

	Controls mean (SD)	Patients mean (SD)	P values (95% CI)	Controls and patients mean (SD)
All gender
Testosterone (ng/ml)	2.27 (2.72)	4.78 (3.67)	P = 0.000 (1.22, 3.79)	3.52 (3.45)
DHEA-S (μg/ml)	238.50 (97.70)	370.70 (146.50)	P = 0.000 (82.78, 181.63)	304.60 (140.60)
Female
TSH (μIU/mL)	1.64 (0.89)	2.46 (1.40)	P = 0.014 (0.17, 1.48)	1.95 (1.17)
Prolactin (ng/ml)	17.79 (7.45)	23.51 (12.00)	P = 0.043 (0.19, 11.24)	19.97 (9.74)
Testosterone (ng/ml)	0.37 (0.16)	0.69 (0.08)	P = 0.001 (0.15, 0.49)	0.49 (0.29)
DHEA-S (μg/ml)	212.07 (86.32)	325.57 (141.78)	P = 0.001 (48.80, 178.19)	255.20 (122.70)
Male
Testosterone (ng/ml)	5.38 (1.91)	7.28 (2.20)	P = 0.003 (0.68, 3.14)	6.56 (2.28)
DHEA-S (μg/ml)	281.60 (102.0)	398.40 (144.60)	P = 0.003 (40.42, 193.07)	354.0 (141.10)

CI: confidence interval, DHEA-S: dihydroepiandrosterone-sulphate, TSH: thyroid stimulating hormone, SD: standard deviation.