International Scholarly Research Notices / 2011 / Article / Tab 2

Clinical Study

Clinical and Morphologic Differences between Class IV-S and Class IV-G Lupus Nephritis

Table 2

Comparison between parameters related to class IV segmental (S) versus global (G) proliferative lupus nephritis (LN).

ParameterClass IV-S LN ( 𝑛 = 4 1 )Class IV-G LN ( 𝑛 = 2 2 )

Cases with all glomeruli affectedNo81,82% (18 biopsies); ( 𝑃 < 0 , 0 0 0 1 )
Number (%) of affected glomeruli473 (76,78%)327 (91,85%); ( 𝑃 < 0 , 0 5 )
Number (%) of cases with membranoproliferative features1 of 41 (2,44%)9 of 22 (40,91%); ( 𝑃 < 0 , 0 0 0 1 )
Percentage of affected glomeruli with fibrinoid necrosis32, 63% (201 glomeruli)20, 78% (74 glomeruli); ( 𝑃 < 0 , 0 1 )
Number (%) of biopsies with fibrinoid necrosis in absence of endocapillary proliferation11 of 29 (37,93%)0 of 22 (0%)
Number (%) of biopsies with capillary hyaline deposits9 of 41 (21,95%)20 of 29 (68,96%); ( 𝑃 < 0 , 0 1 )
Percentage of affected glomeruli with crescents31,82%34,55% ( 𝑃 > 0 , 0 5 )
Number (%) of sclerotic glomeruli174 (28,24%)85 (23,88%); ( 𝑃 < 0 , 0 5 )

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