Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats

Table 3

Effect on Hypericum perforatum on plasma lipid parameters in fructose-fed rats.

Group (𝑛=6)	Total-C (mg/dL)	HDL-C (mg/dL)	LDL-C (mg/dL)	Triglyceride (mg/dL)
Normal control; (normal drinking water + CMC)	81.68 ± 2.36	36.21 ± 1.41	35.98 ± 1.65	47.48 ± 3.15
Fructose control (fructose + CMC)	117.12 ± 5.12***	27.38 ± 1.35***	62.04 ± 4.89**	138.52 ± 4.88***
Fructose + HpE 100 mg/kg	106.01 ± 4.35**	30.12 ± 0.92**	57.25 ± 5.57**	93.24 ± 4.12^***††
Fructose + HpE 200 mg/kg	96.99 ± 4.25^*†	33.69 ± 1.01^†	47.21 ± 4.84	80.50 ± 4.80^***††

^∗𝑃<.05,^∗∗𝑃<.01,^∗∗∗𝑃<.001 versus normal control; ^†𝑃<.01,^††𝑃<.001 versus fructose control.