Clinical Study
Glomerulonephritis with Crescents in Children: Etiology and Predictors of Renal Outcome
Table 5
Factors predicting renal function.
| | Renal function improved | Renal function worsened | |
| Age in years | 13.5 (±5.6) | 8.5 (±1.3) | 0.002 | Globally sclerorsed (GS) glomeruli (%) | 6.4 (±9.3) | 9.3 (±14) | 0.3 | Percent of glomeruli with crescents | 35 (±17) | 59 (±18) | 0.019 | Percent change in proteinuria | −15.2 (13.8) | −8.3 (±12) | 0.2 | Female gender | 85% | 75% | 0.6 | Lupus etiology | 70% | 0% | 0.01 | Significant glomerular infiltrate | 35% | 75% | 0.1 | Significant mesangial cellularity | 10% | 25% | 0.4 | Significant mesangial matrix expansion | 30% | 25% | 0.8 | Significant interstitial fibrosis/atrophy | 10% | 0% | 0.2 | Significant acute tubular necrosis | 25% | 75% | 0.05 | Significant vasculopathy | 5% | 25% | 0.02 |
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