Serum Natrium Determines Outcome of Treatment of Advanced GIST with Imatinib: A Retrospective Study of 80 Patients from a Single Institution

Table 2

Univariate and multivariate analysis of potential prognostic factors affecting overall survival.

	Univariate analysis			Multivariate model
	No. of patients	No. of events	P	No. of patients	HR	P
Gender
Male	51	26
Female	29	16	0.453
PS
0	54	26		45	1
1–3	26	16	0.207	24	1.2	0.627
Concomitant disease
No	45	23
Yes	32	19	0.353
Site of primary tumour
Small intestine	21	10
Other	59	32	0.213
Serum sodium
Normal	55	22		55	1
Low	14	11	<0.01	14	0.3	0.04
Serum LDH
Normal	44	21
Low	29	16	0.846
Serum Hb
Normal	21	8		20	1
Low	52	29	0.099	49	0.7	0.285
Neutrophil count
Normal	57	29
High	16	8	0.745